"You're a nice guy, nice guys may finish last, but the best things in life are worth waiting for."
Since 1 in 10 people don't seem to get the first few panels, here's a rundown:
Twist had a date, he dumped her last minute for Diamond Tiara, Twist then slapped him and ran off.
EDIT: I changed the random male pony that was Twist's date.
Mostly inspired by this picture [link]